yclQ [2017-02-27 15:02:04]

petrobactin (3.4-catecholate siderophore) ABC transporter (binding protein), major component of the secretome

locus: BSU03830

pI: 6.00

mw: 34.00 kDa

protein length: 317 aa

gene length: 951 bp

function: acquisition of iron

product: petrobactin ABC transporter (binding protein)

essential: no

synonyms

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.5|Uptake of iron/ siderophores]
• [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.3|Acquisition of iron] → [category|SW 1.3.3.1|ABC transporters for the uptake of iron/ siderophores]
• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.4|ABC transporters for the uptake of iron/ siderophores]
• [category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|Fur regulon]

Gene

Coordinates on the chromosome (coding sequence): 435,036 -> 435,989

The protein

Catalyzed reaction/ biological activity

• uptake of the siderophore petrobactin [Pubmed|19955416]

Protein family

• Fe/B12 periplasmic-binding domain (according to Swiss-Prot)

Structure

• [PDB|3GFV]

[SW|Localization]

• associated to the membrane (via [protein|552D4C42DCEA4625000160D2625711C61AB11661|FpbN]-[protein|EC63B5CDFDB4DF3A967ECEC40F2C44849311148B|FpbO]) [Pubmed|10092453,18763711]
• extracellular (signal peptide) [Pubmed|18957862]

Expression and Regulation: [[this]]

Biological materials

Mutant

• MGNA-C067 (yclQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2065 NBRP B. subtilis, Japan]

References

• 10092453,19955416,12354229,18957862,18763711,26883633